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PresentationIt is early winter in the United States and a 78-year-old female complains of fever, dry cough, a runny nose, malaise, and achiness for 1 day. Her oxygen saturation is normal and her lungs
are clear. What is the most appropriate next step in management?
What is your diagnosis? A. A chest radiograph to determine therapy B. Oseltamivir 75 mg twice a day for 5 days C. Moxifloxacin 400 mg daily for 5 days D. Amantadine 100 mg twice a day for 5
days
Learnings The recommended treatment for influenza is oseltamivir. Rapid in-office testing is available but is only 50% to 70% sensitive. Treatment should be started without waiting for the
test results.Amantadine is active against influenza A viruses, but not influenza B viruses. There is a high level of resistance to amantadine. Therefore, it is not recommended for antiviral
treatment or prophylaxis.Starting antiviral treatment early in the course of infection decreases morbidity and mortality caused by influenza infection.A chest radiograph would be indicated
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